The left-handed double helical nucleic acids.
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چکیده
منابع مشابه
The left-handed double helical nucleic acids.
The conversion of right-handed dsDNA and dsRNA to the left-handed Z-conformation involves a reorganization of the nucleotides relative to each other. This conversion can be facilitated by the tight binding of a Z-conformation-specific protein domain from the editing enzyme dsRNA adenosine deaminase. This may influence the modification of both pre-mRNAs as well as some replicating RNA viruses.
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Helical double stranded polymers incorporated with a covalently bound chiral ferrocene linker are synthesised and characterized by CD spectra and STM images and molecular dynamics simulations.
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The conformational behaviour of delta Ala has been investigated by quantum mechanical method PCILO in the model dipeptide Ac-delta Ala-NHMe and in the model tripeptides Ac-X-delta Ala-NHMe with X = Gly, Ala, Val, Leu, Abu and Phe and is found to be quite different. The computational results suggest that in the model tripeptides the most stable conformation corresponds to phi 1 = -30 degrees, ps...
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Infinite square-tubular helices, [CuCl2(L)(S)] (L = bis(4-pyridyl)methylvinylsilane; S = Me2SO, HCONMe2), were constructed. This helical system affords three kinds of P, M crystals in Me2SO, and racemic crystals in HCONMe2. The cyclic voltammogram (CV) technique using the M-crystals is an effective tool for discerning the chirality of proline.
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2001
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2001_3916